BIZIT

FEEL the woRld BeYonD

It takes a third person, sometimes a complete stranger, to give a fresh perspective to life, things, ideas, to complete the incomplete", :x, Please share me your stories|--Quotes Today:-Whatever happened, it happened for good. Whatever is happening, is happening for good. Whatever that will happen, it will be for good. What have you lost for which you cry? What did you bring with you, which you have lost? What did you produce, which has destroyed? You did not bring anything when you were born. Whatever you have, you have received from Him. Whatever you will give, you will give to Him. You came empty handed and you will go the same way. Whatever is yours today was somebody else’s yesterday and will be somebody else’s tomorrow. Change is the law of the universe.--|

ॐ There is no cure

Published by The Name is Bizit | under on 6:31 PM
Fibrodysplasia Ossificans Progressiva (FOP for short) is a very rare disease that causes parts of the body (muscles, tendons, and ligaments) to turn to bone when they are damaged. This can often cause damaged joints to fuse together, preventing movement. Unfortunately surgical removal of the bone growths is ineffective as the body “heals” itself by recreating the removed bone. To make matters worse, the disease is so rare that it is often misdiagnosed as cancer, leading doctors to perform biopsies which can spark off worse growth of these bone-like lumps.FOP is a genetic disease. The bone growth progresses from the top downward, just as bones grow in fetuses. A child with FOP will typically develop bones starting at the neck, then on the shoulders, arms, chest area and finally on the feet. However it does not necessarily occur in this order due to injury-caused flare-ups. Often, the tumor-like lumps that characterize the disease appear suddenly. The gene that causes ossification is normally deactivated after a fetus' bones are formed in the womb, but in patients with FOP, the gene keeps working. Aberrant bone formation in patients with FOP occurs when injured connective tissue or muscle cells at the sites of injury or growth incorrectly express an enzyme for bone repair during apoptosis (self-regulated cell death), resulting in lymphocytes containing excess bone morphogenetic protein 4 (BMP4) provided during the immune system response. Since the incorrect enzyme remains unresolved within the immune response, the body continues providing the incorrect BMP4-containing lymphocytes. BMP4 is a product that contributes to the development of the skeleton in the normal embryo.
The most famous case is Harry Eastlack whose body was so ossified by his death that he could only move his lips. His skeleton is now on display at the Mütter Museum. 


There is no cure.

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